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Vacor, or N-3-pyridylmethyl-N-p-nitrophenyl urea (PNU), is a chemical used as a rodenticide. It is structurally related to nicotinamide. Exposure to vacor usually occurs by accidental or intentional ingestion. Classification. Vacor causes a severe acute distal axonopathy after even a single exposure. There is also significant autonomic involvement.
Vacor entered the market in 1975 as a "safe" rodenticide. While Vacor is the brand name, its chemical name is N-3 pyridylmethyl-N' 4 nitrophenyl urea. It also goes by the names PNU, Pyriminil, Pyrinuron, …
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A case of N-3 pyridylmethyl-N' 4 nitrophenyl urea (Vacor) rodenticide poisoning in a 52-year-old man is presented. Vacor is structurally related to alloxan and streptozotocin, agents that have been used extensively to produce diabetes mellitus in laboratory animals. Seven days after ingestion of Vac …
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Harold E. Lebovitz, in Endocrinology: Adult and Pediatric (Seventh Edition), 2016 Drugs That Affect β Cell Function. Pentamidine and pyriminil (Vacor) are substances that resemble streptozotocin and alloxan chemically.Pentamidine is an antiprotozoal agent that is used extensively to treat Pneumocystis carinii infection. Pyriminyl is a nitrosourea-derived …
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Vacor, or N-3-pyridylmethyl-N-p-nitrophenyl urea (PNU), is a chemical used as a rodenticide. It is structurally related to nicotinamide. Exposure to vacor usually occurs by …
Vacor entered the market in 1975 as a "safe" rodenticide. While Vacor is the brand name, its chemical name is N-3 pyridylmethyl-N' 4 nitrophenyl urea. It also goes …